منابع مشابه
Plugging PKA into ERK scaffolds.
Cancers often arise in part through derangements in protein kinase signaling. A striking example of this is the finding that approximately 30% of human tumors have mutations in Ras or B-Raf, leading to aberrant ERK kinase activation. Kinase signaling networks are often organized by scaffolding and anchoring proteins that help shape the dynamics of signal processing. AKAP-Lbc associates with the...
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In North America, electricity prices exhibit both temporal and geographic variation—the later exists due to regional demand differences, transmission inefficiencies and generation diversity. Using historical market data, we characterize the variation and argue that existing distributed systems should be able to exploit it for significant economic gains. We consider pricing in cloud computing sy...
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Advances in hardware, software, and coding standards for digital media have now made the delivery of multimedia information a standard component of many systems. Unfortunately, the pace of this technological development, coupled with strong commercial competition between leading vendors, has meant that little consensus has emerged over the design of programming interfaces to allow the creation,...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2011
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.10.5.14902